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San Francisco is 4-0 because Kyle Shanahan can still reach for a different answer when the easy offense disappears. Brock Purdy threw two more touchdowns without an interception, Christian McCaffrey punched in a score and George Kittle broke the game open with a 56-yard screen against Denver. Just as important, the defense bottled up Bo Nix for three quarters. The 49ers are winning with both the stars and the structure around them.
San Francisco's wide-zone and play-action identity is producing enough offense to carry more of the weekly burden. The 49ers scored 36 against Arizona and moved to 3-0, giving Brock Purdy and the offense room to keep winning even when the defense allows more than the preferred script.
Pressure Point
San Francisco Has to Keep Its Veteran Core Available
San Francisco has to preserve the clean timing it showed against Miami. Purdy does not need to hunt explosives when the run game, Kittle and the intermediate passing game keep producing favorable downs, but injuries can still narrow those answers quickly.
PFM CALLLocks October 4th at 4:25 PM EDT
Who wins Denver Broncos vs. San Francisco 49ers?
Week 4 matchup
AwayDEN2-2
AT
HomeSF4-0
Pick the winner.
FINAL RESULTSan Francisco 49ersThis Call is settled.
PFM's CallSan Francisco 49ers
Final ResultSan Francisco 49ers
PFM ROAD AHEAD
2026 San Francisco 49ers Remaining Strength of Schedule
San Francisco owns one of the tougher remaining roads in the league because Los Angeles Rams, Los Angeles Chargers and Kansas City Chiefs form the hardest part of it. PFM has the schedule No. 7 with an opponent average of 81.0 and 4 games against current top-10 teams. The road is not difficult from start to finish, but the stretch around Los Angeles Rams, Los Angeles Chargers and Kansas City Chiefs leaves little room for an off week.
Difficulty Rank#7No. 1 is toughest
Remaining Opponent Avg.81.0Average across opponents
San Francisco supports the quarterback with wide zone and play action, while Los Angeles Rams get there with its offensive structure. That means San Francisco can use run action to create a cleaner passing window, while Los Angeles Rams can keep the down manageable before the quarterback has to create. Offense is the main separator because San Francisco has a stronger answer through wide zone and play action after a defense removes the preferred call.
Seattle and the Rams both enter with deeper recent proof in the NFC West. San Francisco can stay in the race by staying on schedule with the run game, creating easy throws for Purdy and letting the front attack a predictable passer. The remaining problem is age and injury risk across a roster that still depends on several veteran stars.
Trent Williams remains San Francisco's left tackle, but succession planning cannot wait at this stage of his career. The 49ers need a tackle who can develop into the next blind-side protector for Brock Purdy.
CBModerate Priority
Renardo Green and Deommodore Lenoir start outside, but the live roster lists only seven corners. Another cover player would give San Francisco better injury protection and matchup flexibility.
IOLSecondary Need
Connor Colby and Dominick Puni currently start at guard around Jake Brendel. Adding another interior blocker would strengthen depth and help the offense prepare for turnover around its veteran center.