De'Zhaun StriblingMeaningful impact
Stribling's multiweek absence removes a young receiver from a San Francisco group already missing Ricky Pearsall for the season.
Roster StrengthOffense Rating
PFM NFL Injury Tracker
2026 San Francisco 49ers Injury Report
The 2026 San Francisco 49ers injury report currently has 14 players still being tracked. The latest San Francisco 49ers injury update is De'Zhaun Stribling, currently listed as Injured.
Last updated:
Upcoming Game Status
Latest verified practice participation and game designations for this matchup.
Week 2 · vs. Miami Dolphins · Sep 20
No verified practice or game designations are listed yet for this matchup.
Current San Francisco 49ers Injuries
14 current
De'Zhaun StriblingWR
Injured
deltoid ankle sprain
Alfred CollinsDT IRtorn patellar tendon
James Thompson Jr.DL Monitoringhamstring
Sam OkuayinonuDE IRFoot
Mike EvansWR ReturnedAdductor
Nick BosaDE ReturnedKnee
Isaac GuerendoRB PUPpectoral
Christian KirkWR IRInjury update
Austen PleasantsOL IRInjury update
Mykel WilliamsDL PUPknee
Patrick TaylorRB IRInjury update
Victor DimukejeDL IRInjury update
Christian McCaffreyRB ReturnedTightness
Deommodore LenoirCB ReturnedShoulder
PFM Impact on San Francisco 49ers
James Thompson Jr.Meaningful impact
Thompson's availability matters more after San Francisco lost Alfred Collins for the season and entered Week 1 with defensive-line depth already under pressure. PFM will monitor Defense and Roster Strength through game-day inactives.
Roster StrengthDefense Rating
Sam OkuayinonuMeaningful impact
Okuayinonu's move to IR turns San Francisco's edge-depth question into a multi-week issue on a defense PFM already grades as the team's weakest core area. PFM will review Defense and Roster Strength with Khalid Kareem joining the rotation as the immediate replacement.
Roster StrengthDefense Rating
Latest San Francisco 49ers Injury Updates
De'Zhaun Stribling Expected to Miss at Least a Month
De'Zhaun Stribling has a deltoid sprain in his ankle and is expected to miss at least a month.
De'Zhaun Stribling's Achilles Intact After Left Ankle Injury
De'Zhaun Stribling injured his left ankle in San Francisco's Week 1 win over the Rams and was ruled out. Kyle Shanahan said his Achilles is intact, and Stribling will undergo further medical testing on the ankle.
Alfred Collins Placed on Season-Ending Injured Reserve
San Francisco placed Alfred Collins on season-ending injured reserve on September 10th after his torn patellar tendon.
James Thompson Jr. Questionable for Week 1
James Thompson Jr. is questionable for Week 1 with a hamstring injury after returning from a missed Tuesday practice to work on a limited basis Wednesday and Thursday.
Luke Gifford Returns to Full Practice
Luke Gifford returned to full practice on September 10th after being limited Tuesday and Wednesday with a hamstring injury. He has no Week 1 game designation.
Renardo Green Returns to Full Practice
Renardo Green returned to full practice on September 10th after being limited Tuesday and Wednesday with a hamstring injury. He has no Week 1 game designation.
Dre Greenlaw Returns to Full Practice
Dre Greenlaw returned to full practice on September 10th after being limited Tuesday and Wednesday with Achilles discomfort. He has no Week 1 game designation.
Gracen Halton Returns to Full Practice
Gracen Halton returned to full practice on September 10th after being limited Tuesday and Wednesday with an ankle injury. He has no Week 1 game designation.
Romello Height Returns to Full Practice
Romello Height returned to full practice on September 10th after being limited Tuesday and Wednesday with an ankle injury. He has no Week 1 game designation.
George Kittle Clears Week 1 Injury Report
George Kittle was limited in all three practices in Melbourne but has no game designation for Week 1 against the Rams.
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