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PFM NFL Injury Tracker

2026 San Francisco 49ers Injury Report

The 2026 San Francisco 49ers injury report currently includes 4 active injuries. The latest San Francisco 49ers injury update is Christian McCaffrey, currently listed as Returned.

Latest team update:

Current San Francisco 49ers Injuries

4 current

PFM Impact on San Francisco 49ers

Christian McCaffreyMeaningful impact

San Francisco gets McCaffrey back into full-team work as the offense gets healthier before Week 1. His return is key as it will officially put to rest rumors of him holding out from the team.

Roster StrengthOffense Rating
George KittleMeaningful impact

Kittle's activation removes the risk of an automatic four-game PUP absence and gives San Francisco a path to restoring a core piece of the passing game. PFM will wait for full-team work before treating Week 1 as settled.

Roster StrengthOffense Rating
Deommodore LenoirLimited impact

San Francisco gets an experienced corner back on the field, even if the non-contact jersey shows the shoulder issue is not fully behind him. The return improves secondary depth without changing the defense's overall evaluation yet.

Roster StrengthDefense Rating

Latest San Francisco 49ers Injury Updates

Christian McCaffrey

Christian McCaffrey returns to 49ers practice

Christian McCaffrey returned to practice Sunday after missing multiple weeks with tightness. He participated in team drills and said the time away was part of his planned workload management.

De'Zhaun Stribling

De'Zhaun Stribling returns to practice

De'Zhaun Stribling returned to 49ers practice Sunday after missing Saturday with a shoulder injury. He worked in a non-contact jersey.

George Kittle

George Kittle activated from PUP

San Francisco activated George Kittle from the physically unable to perform list Sunday. Kittle returned to practice in full pads for individual work but did not participate in team drills.

Deommodore Lenoir

Deommodore Lenoir returns to practice

Deommodore Lenoir returned to 49ers practice Sunday after missing Saturday with a shoulder injury. He worked in a non-contact jersey.

De'Zhaun Stribling

De'Zhaun Stribling day to day with shoulder injury

De'Zhaun Stribling is considered day to day with a shoulder injury. No more specific diagnosis or return date was reported.

Deommodore Lenoir

Deommodore Lenoir day to day with shoulder injury

Deommodore Lenoir is considered day to day with a shoulder injury. No more specific diagnosis or return date was reported.

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