San Francisco 49ers
Tracking 16 players with current injury reports. Check the upcoming matchup and player updates below.
Last updated:
Latest verified practice participation and game designations for this matchup.
Week 9 · vs. Las Vegas Raiders · Nov 8
No verified practice or game designations are listed yet for this matchup.
mild hamstring strain
Deebo SamuelWR Injuredhamstring
Garret WallowLB Injuredhamstring
Marques SigleS Injuredankle
Nick BosaDE Injuredknee and calf
Luke GiffordLB Injuredgroin
Mike EvansWR Injuredribs and Achilles
Siran NealS Monitoringknee
Upton StoutCB Monitoringshoulder
De'Zhaun StriblingWR IRdeltoid ankle sprain
Jake TongesTE IRknee
Alfred CollinsDT IRtorn patellar tendon
Sam OkuayinonuDE IRFoot
Isaac GuerendoRB Injuredpectoral
Austen PleasantsOL IRInjury update
Victor DimukejeDL IRInjury update
San Francisco has its bye to protect McCaffrey's lead rushing and receiving role while his hamstring recovers. Kaelon Black handled backup carries against Atlanta, giving the 49ers a current alternative if McCaffrey's workload needs to be reduced after the break.
San Francisco loses one of its most versatile receivers against Atlanta while Mike Evans is also out. The 49ers must replace Samuel's short-area catches and designed touches, limiting the ways Brock Purdy can get the ball into space.
San Francisco must face Atlanta without its top edge rusher. Bosa's absence reduces the 49ers' ability to create pressure without extra rushers and puts more responsibility on the rest of the defensive front.
Kyle Shanahan confirmed that Christian McCaffrey sustained a mild hamstring strain against Atlanta and expressed optimism about his recovery during San Francisco's Week 8 bye.
Gracen Halton was cleared on October 25, 2026. Gracen Halton was absent from San Francisco's Week 7 final injury report and was not among the 49ers' inactive players against Atlanta.
Christian McCaffrey returned to San Francisco's Week 7 game against Atlanta in the third quarter after leaving with a thigh injury.
San Francisco activated Christian Kirk from injured reserve Saturday ahead of its game against Atlanta.
San Francisco ruled out Deebo Samuel against Atlanta with a hamstring injury.
San Francisco ruled out Nick Bosa against Atlanta with knee and calf injuries.
San Francisco ruled out Marques Sigle against Atlanta with an ankle injury.
San Francisco ruled out Garret Wallow against Atlanta with a hamstring injury.
San Francisco ruled out Mike Evans against Atlanta after he missed the week's practices with rib and Achilles injuries.
Christian Kirk practiced fully all week but is questionable for San Francisco's game against Atlanta while returning from a calf injury.