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Nick Bosa Injury Update

SFDE

Last updated:

Nick Bosa is out for Week 5 against Seattle with knee and calf injuries.

Current Status

StatusInjured
Injuryknee/calf
Practice—
Game status—

PFM Impact

Major impact
Ratings affected
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San Francisco loses its premier outside pass rusher against Seattle. The remaining edge defenders must create pressure without Bosa while the 49ers adjust their pass-rush rotation.

Injury timeline

Nick Bosa Injury History

7 updates · Latest October 9, 2026

Nick Bosa Out for Week 5

knee/calf · Game: Out (Week 5 vs. SEA)

Nick Bosa is out for Week 5 against Seattle with knee and calf injuries.

Sources
View 4 older injury updates

Nick Bosa Misses Thursday Practice

Practice: DNP · Bosa did not practice Thursday on San Francisco's Week 3 injury report.

Nick Bosa did not practice Thursday ahead of San Francisco's Week 3 game against Arizona.

Sources

Nick Bosa Returns to 49ers Practice

Knee · Practice: Returned to practice Wednesday · Returned to practice · Return: Bosa expects to play in Week 1 against the Rams

Nick Bosa returned to practice on September 2nd for the first time since August 3rd. Bosa said he expects to play in Week 1 against the Rams.

Sources
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