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Isaac Guerendo Injury Update

SFRB

Last updated:

The San Francisco 49ers placed Isaac Guerendo on Reserve/PUP on August 30, ruling him out for at least the first four games.

Current Status

Game availability at DAL Week 10 · November 15, 2026
Game designation No verified designation yet
StatusInjured
Injurypectoral
Verified Sources

PFM Impact

Limited impact
Ratings affected
Roster StrengthOffense Rating

Guerendo's PUP move trims the early depth behind Christian McCaffrey, but San Francisco has other healthy backs available. PFM will treat it as a real depth loss rather than a major offensive change.

See the San Francisco 49ers PFM ratings

PFM depth chart

Where Isaac Guerendo Fits

PositionRunning Back
  1. 01 Christian McCaffrey
  2. 02 Kaelon Black
  3. 04 Isaac Guerendo No. 4 on depth chart
View team depth chart
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